Recall that fatty acids (like palmitic acid) can yield substantially more ATP when compared with glucose. Why doesn't aerobic respiration rely solely on fatty acids as energy sources, rather than glucose?
A) Aerobic respiration usually does rely on fatty acids in other mammals; however, humans are unique due to their relatively recent appearance on Earth.
B) Fatty acids cannot be used by some vital tissues in the human body, such as the brain.
C) Beta-oxidation-the process by which fatty acids are broken down-requires a great deal of ATP and is not an energy-efficient process for cells.
D) Fatty acids cannot be used to generate acetyl-CoA, and so cannot tie into the later stages of aerobic respiration.
E) Fatty acids are rare in the environment and cannot be readily acquired from food sources.
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