The mechanisms underlying the development of cardiac hypertrophy are complex,although relaxation abnormalities that result in chronic elevation of cytosolic Ca++ level appear to promote the development of hypertrophy through:
A) Stimulation of the sarcolemmal Ca++ pump.
B) Ca++ binding to troponin I.
C) Activation of calcineurin.
D) Inhibition of Ca++/calmodulin-dependent protein kinase.
E) Opening of Ca++-activated K+ channels.
Correct Answer:
Verified
Q1: Cardiac muscle cells in the atria are
Q2: Calsequestrin in cardiac muscle:
A)Acts as a high-affinity
Q3: Relaxation of cardiac muscle typically requires:
A)Myosin light-chain
Q4: Epinephrine increases the force of contraction of
Q5: The force of contraction of cardiac muscle
Q6: Contraction of cardiac muscle typically requires:
A)Ca++ influx
Q7: Mutations in the cardiac ryanodine receptor have
Q8: Stretching cardiac muscle results in an increase
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