Which level of protein structure is disrupted upon mild heating or alteration in pH?

Question

Quizplus · Accepted Answer

Mild heating or alteration in pH can disrupt the weak interactions (such as hydrogen bonds, ionic bonds, and hydrophobic interactions) that maintain the tertiary structure of a protein, resulting in a loss of its three-dimensional shape and function. The primary structure (sequence of amino acids) and the secondary structure (alpha helices, beta sheets) are more stable and typically not affected by mild alterations.

Which Level of Protein Structure Is Disrupted Upon Mild Heating