Patients with colon cancer often exhibit loss of heterozygosity at specific chromosomal arms.These chromosomal regions most likely include genes that act as
A)Pro-apoptotic genes.
B)Oncogenes.
C)Tumor suppressors.
D)Tumor promoters.
E)None of the above.

Question

Quizplus · Accepted Answer

Loss of heterozygosity at specific chromosomal arms is often associated with inactivation of tumor suppressor genes. Therefore, the most likely chromosomal regions affected in colon cancer are those containing tumor suppressor genes, making choice C the best option.

Patients with Colon Cancer Often Exhibit Loss of Heterozygosity at Specific