Transformation of some types of human cells has been achieved through insertion of cloned genes coding for
A)Oncogenic H-Ras alone.
B)SV40 early region and hTERT together.
C)SV40 early region and oncogenic H-Ras together.
D)hTERT and oncogenic H-Ras together.
E)Oncogenic H-Ras,SV40 early region,and hTERT together.

Question

Quizplus · Accepted Answer

Transformation of human cells requires multiple steps, including the activation of telomerase (hTERT), inhibition of tumor suppressors (SV40 early region), and activation of oncogenes (oncogenic H-Ras). Therefore, the most effective transformation would require the insertion of all three genes together (option E).

Transformation of Some Types of Human Cells Has Been Achieved