Sporadic cases of retinoblastoma require
A) One inactivating somatic mutation in one copy of Rb.
B) Two somatic inactivating mutations,one in each of the two copies of Rb.
C) One somatic mutation in Rb,leading to its activation.
D) Two somatic mutations in a copy of Rb,leading to its activation.
E) None of the above.
Correct Answer:
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