You are studying a cell line in which the loss of just one copy of a tumor suppressor gene provides a growth advantage for the cells.This would be an example of genetic

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Haploinsufficiency is a genetic condition in which one copy of a gene is not sufficient to provide a normal function or phenotype, leading to a partial loss of function. In the context of a tumor suppressor gene, loss of one copy (also known as a heterozygous mutation) can provide a growth advantage for the cells, making them more prone to develop into a cancerous state. Haplosufficiency refers to a condition in which one copy of a gene is enough to provide a normal function, while heteroinsufficiency is a genetic condition in which the different alleles of a gene have different levels of function, leading to a partially impaired phenotype when two different alleles are present. Unilateral mutation is not a recognized genetic term.

You Are Studying a Cell Line in Which the Loss