Chronic granulomatous disease (CGD),a condition resulting in chronic bacterial and fungal infections,is caused by one or more defects in _____,compromising the ability of macrophages to _____.

Question

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Chronic granulomatous disease (CGD) is caused by defects in the NADPH oxidase enzyme, compromising the ability of macrophages to produce reactive oxygen species (ROS) such as superoxide, which are important in destroying bacteria and fungi. Without ROS, the immune system is unable to control infections, leading to chronic bacterial and fungal infections in CGD patients.

Chronic Granulomatous Disease (CGD),a Condition Resulting in Chronic Bacterial and Fungal