During a secondary immune response,high-affinity IgG antibodies are produced.Which of the following best explains why low-affinity IgM antibodies are not made?
A) Naive pathogen-specific B cells are suppressed by negative signaling through FcγRIIB1.
B) Naive pathogen-specific B cells isotype switch and hypermutate much more quickly during secondary immune responses.
C) Memory B cells outnumber naive B cells.
D) Low-affinity IgM antibodies are made only when antigen concentration is exceedingly high.
Correct Answer:
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