What is the fate of centrocytes in which somatic hypermutation has resulted in high-affinity receptors for antigen? (Select all that apply.)
A) They die by apoptosis.
B) They express Bcl-xL.
C) They process antigen and present it to TFH cells.
D) CD40 on the centrocyte engages with CD40 ligand on TFH cells.
E) They undergo phagocytosis by tingible body macrophages.
Correct Answer:
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Q4: Engulfment of apoptotic centrocytes is facilitated by
Q5: To mount the most effective antibody response
Q6: B cells migrating directly from a primary
Q7: Immunoreceptor tyrosine-based activation motifs (ITAMs)are located on
Q8: Which of the following statements is true
Q10: If a centrocyte does not interact with
Q11: Lymphoblasts upregulate a transcription factor called _
Q12: A primary focus of clonal expansion is
Q13: Plasma cells and memory B cells differentiate
Q14: _ in the switch regions positioned 5′
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