Which of the Following Processes Is Not Dependent on an Interaction

Which of the following processes is not dependent on an interaction involving MHC class I or class II molecules? (Select all that apply.)

A) positive selection of α:β T cells
B) intracellular signaling by pre-T-cell receptors
C) negative selection of αβ T cells
D) peripheral activation of mature naive T cells
E) positive selection of γ:δ T cells.