Which of the following statements regarding positive selection is correct?
A) All subsets of developing T cells undergo positive selection before export to the peripheral circulation.
B) T-cell receptor editing is linked to the process of positive selection.
C) Positive selection results in the production of T cells bearing T-cell receptors that have the capacity to interact with all allotypes of MHC class I and class II molecules,and not just those of the individual.
D) Positive selection ensures that autoreactive T cells are rendered non-responsive.
E) If there is a genetic defect in AIRE,then T-cell development is arrested as positive selection commences.
Correct Answer:
Verified
Q2: Genetic deficiencies in all of the following
Q3: Which of the following statements about Notch
Q4: Which of the following processes is not
Q5: If a double-negative thymocyte has just completed
Q6: Thymocytes that are not positively selected
A)undergo genetic
Q7: Which of the following is mismatched:
A)double-negative CD3-
Q8: Which of the following statements are true
Q9: Which of the following is the first
Q10: In which of the following ways does
Q11: _ of thymocytes is necessary to produce
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