Which of the following statements is TRUE?
A)In general,inversion and translocation heterozygotes are as fertile as organisms whose chromosomes are in the standard arrangement.
B)Inversions and translocations are without evolutionary significance.
C)Translocations may be pericentric or paracentric.
D)Individuals with familial Down syndrome are trisomic and have 47 chromosomes.
E)Familial Down syndrome is caused by a translocation involving chromosome 21.

Question

Quizplus · Accepted Answer

Familial Down syndrome is caused by a translocation involving chromosome 21. This translocation results in the inheritance of an extra copy of some or all of chromosome 21, leading to Down syndrome. The other answer choices are false: A) Inversion and translocation heterozygotes may have reduced fertility due to problems with pairing of chromosomes during meiosis. B) Inversions and translocations can have evolutionary significance, such as creating new gene arrangements or driving speciation. C) Translocations may be pericentric (involving the centromere) or paracentric (not involving the centromere). D) Individuals with Down syndrome have an extra copy of chromosome 21, resulting in 47 chromosomes.

Which of the Following Statements Is TRUE