A patient's symptoms include visual impairment, headache, dizziness, and deafness. The peripheral blood smear reveals lymphoplasmacytic lymphoma. What would rule out the diagnosis of Waldenström's macroglobulinemia?

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The symptoms described are consistent with Waldenström's macroglobulinemia. Elevated plasma levels of IgM, increased serum viscosity levels, or the presence of monoclonal κ light chains would support the diagnosis. The presence of plasma cell neoplasm with lytic bone lesions would be more consistent with multiple myeloma and would rule out Waldenström's macroglobulinemia as a diagnosis.

A Patient's Symptoms Include Visual Impairment, Headache, Dizziness, and Deafness