A bone marrow differential is performed on a patient suspected of having leukemia. Cytochemical stains are performed. MPO and SBB are negative. Blasts appear homogeneous and small in size. What would you expect to find when performing immunophenotyping?
A) Positive reactivity with immature B-cell or T-cell markers
B) Positive reactivity with immature myeloid markers
C) Positive reactivity with mature myeloid markers
D) Positive reactivity with plasma cell markers

Question

Quizplus · Accepted Answer

Since MPO and SBB are negative and the blasts appear small and homogeneous, they are likely to be lymphoid blasts. Therefore, immunophenotyping would be expected to show positive reactivity with immature B-cell or T-cell markers.

A Bone Marrow Differential Is Performed on a Patient Suspected