A gene involved in regulating the growth of myeloid cells is hypermethylated, resulting in a block in transcription. This is an example of malignancy as a result of:
A) Post-translational modification
B) DNA mutation
C) Epigenetic change
D) Genomic instability

Question

Quizplus · Accepted Answer

Hypermethylation is an example of an epigenetic change, where the DNA sequence itself is not mutated, but the regulation of gene expression is altered.

A Gene Involved in Regulating the Growth of Myeloid Cells