An oncologist has a patient with dihydropyrimidine dehydrogenase deficiency. Which of the following is a chemotherapy agent that the doctor should be cautious about using with this patient because of serious side effects?
A) "primaquine"
B) "$\beta$-alanine"
C) "5-dihydrothymine"
D) "5-fluorouracil"

Question

Quizplus · Accepted Answer

Patients with dihydropyrimidine dehydrogenase deficiency have a higher risk of serious side effects, including life-threatening toxicity, when treated with chemotherapy agents like 5-fluorouracil. Therefore, the oncologist should be cautious about using this drug with the patient.

An Oncologist Has a Patient with Dihydropyrimidine Dehydrogenase Deficiency β\betaβ -Alanine" C) "5-Dihydrothymine" D) "5-Fluorouracil

An Oncologist Has a Patient with Dihydropyrimidine Dehydrogenase Deficiency $\beta$ -Alanine"
C) "5-Dihydrothymine"
D) "5-Fluorouracil