Which enzyme activity would be directly reduced if fluorodeoxyuridine-5 ^' -monophosphate is present? A) thymidine kinase B) thymidylate synthase C) dihydrofolate reductase D) serine hydroxymethyltransferase

Question

Quizplus · Accepted Answer

Fluorodeoxyuridine-5F1F1F1S1^F1F1F10-monophosphate is an inhibitor of thymidylate synthase, which is the enzyme responsible for catalyzing the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), a key step in DNA synthesis. Therefore, if this inhibitor is present, thymidylate synthase activity would be directly reduced.

Which Enzyme Activity Would Be Directly Reduced If Fluorodeoxyuridine-5 '

Which Enzyme Activity Would Be Directly Reduced If Fluorodeoxyuridine-5 ^'