Which of the Following Statements About IPS Cells Is FALSE

Which of the following statements about iPS cells is FALSE?

A) iPS cells can be made by adding a combination of transcription regulators to a fibroblast.
B) iPS cells made from mouse cells can differentiate into almost any human cell type.
C) Stimulation by extracellular signal molecules causes iPS cells to differentiate.
D) A cell that is dedifferentiated to become an iPS cell will undergo changes to its gene expression profile.