A scientist might create a conditional knockout of a mouse gene when
A)a homozygous loss-of-function mutation in the gene causes embryonic lethality.
B)a homozygous loss-of-function mutation in the gene produces a wild-type phenotype.
C)a homozygous loss-of-function mutation in the gene affects only ears.
D)a homozygous loss-of-function mutation in the gene affects only coat color.

Question

Quizplus · Accepted Answer

Conditional knockouts allow researchers to delete genes in specific tissues or at specific times in development. This is particularly useful when a homozygous loss-of-function mutation in the gene causes embryonic lethality, as it enables the study of the gene's function beyond the embryonic stage.

A Scientist Might Create a Conditional Knockout of a Mouse