LHON is a rare mitochondrial disease caused by weak hypomorphic mutations that affect the mitochondrial electron transport chain.The first symptoms of the disease include blindness.People with LHON are usually homoplasmic because retinas must be homoplasmic mutant for a person to have disease symptoms.Which is true about a male who is heteroplasmic for the mutation that causes LHON? (Select all that apply. )
A)He is likely to develop the disease in other parts of his body.
B)He may have children who are blind due to LHON.
C)All of his children will most likely be homoplasmic for the wild-type mitochondria.
D)Some cells in his body are probably homoplasmic.

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The Answer of LHON is a rare mitochondrial disease caused by weak hypomorphic mutations that affect the mitochondrial electron transport chain.The first symptoms of the disease include blindness.People with LHON are usually homoplasmic because retinas must be homoplasmic mutant for a person to have disease symptoms.Which is true about a male who is heteroplasmic for the mutation that causes LHON? (Select all that apply. )
A)He is likely to develop the disease in other parts of his body.
B)He may have children who are blind due to LHON.
C)All of his children will most likely be homoplasmic for the wild-type mitochondria.
D)Some cells in his body are probably homoplasmic.

LHON Is a Rare Mitochondrial Disease Caused by Weak Hypomorphic