Each human α-globin locus contains two α-globin genes, α1 and α2, and most individuals have two copies of the locus.Which of the genotypes would result in the most severe phenotype? (A"-" represents a deletion allele. ) A)α1 α1 / α2 α2 B)α1 - / α2 - C)α1 α1 / - - D)α1- / α2 α2 E)α1 - / - -

Question

Quizplus · Accepted Answer

E) α1 - / - - represents a genotype with three deletions in the α-globin genes, which would result in a more severe phenotype due to a greater reduction in α-globin production compared to the other genotypes listed.

Each Human α-Globin Locus Contains Two α-Globin Genes, α1 and α2