A plaque reduction neutralization assay is performed with a patient serum. The presence of abundant plaques on the plate indicates that the patient is currently infected with the virus in question.

Question

Quizplus · Accepted Answer

The presence of abundant plaques in a plaque reduction neutralization assay indicates that the patient's serum is not effectively neutralizing the virus, not necessarily that the patient is currently infected. This assay measures the ability of antibodies in the serum to neutralize the virus, not the presence of the virus itself.

A Plaque Reduction Neutralization Assay Is Performed with a Patient