What Happened as Trade Expanded Following Alexander the Great's Conquests

What happened as trade expanded following Alexander the Great's conquests?

A) Traders traveled across the entire Silk Road to sell their products in distant lands.
B) The effectiveness of new land routes inhibited the development of maritime commerce.
C) The early culture/societies of Egypt and Mesopotamia lost their preeminence as sources of innovation and knowledge.
D) Southeast Asia, especially the islands of Indonesia, remained disconnected from the trade networks linking Afro-Eurasia.