When the activity of REM-on neurons and acetylcholine levels reach a high level the characteristic features of slow-wave NREM sleep reemerge and there is reduced brain and physiological activity and increased levels of sleep thinking.

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When the activity of REM-on neurons and acetylcholine levels reach a high level, it leads to the characteristic features of REM sleep, including increased brain and physiological activity, reduced muscle tone, and heightened dream activity. Slow-wave NREM sleep is characterized by delta waves on EEG and is associated with deep physical and mental rest rather than increased levels of "sleep thinking."

When the Activity of REM-On Neurons and Acetylcholine Levels Reach