Why have most clinical trials in which retroviruses have been used to introduce genes for the purpose of gene therapy in patients lacking that gene been unsuccessful?
A)Viral DNA is more unstable than mammalian DNA.
B)Current viral vectors have too high an infection efficiency rate.
C)Current viral vectors have too low an infection efficiency rate.
D)Mammalian DNA is more unstable than viral DNA.
E)Current viral vectors tend to cause serious diseases.

Question

Quizplus · Accepted Answer

Current viral vectors have too low an infection efficiency rate, which means that not enough cells are receiving the therapeutic gene. This can limit the effectiveness of the treatment.

Why Have Most Clinical Trials in Which Retroviruses Have Been