Where are misfolded secretory proteins eventually destroyed?
A)in the RER
B)in the SER
C)in the Golgi complex
D)in the cytosol (cytoplasm)
E)in the nucleus

Question

Quizplus · Accepted Answer

Misfolded secretory proteins are recognized and removed by quality control mechanisms in the endoplasmic reticulum (ER). If they cannot be properly folded or repaired, they are retrotranslocated to the cytosol where they are polyubiquitinated and targeted for degradation by the proteasome.

Where Are Misfolded Secretory Proteins Eventually Destroyed