The accumulation of misfolded proteins in the ER is a potentially lethal situation and thus causes the triggering of what process?
A)the unfolded protein response (UPR)
B)the posttranscriptional response
C)the polysomal response
D)the proteasomal response
E)the intracellular protein response

Question

Quizplus · Accepted Answer

The accumulation of misfolded proteins in the ER triggers the unfolded protein response (UPR), which is a protective stress response that aims to restore proper folding and function of proteins in the ER. Failure to restore ER homeostasis through the UPR can lead to cell death. The other options are not relevant to this specific situation.

The Accumulation of Misfolded Proteins in the ER Is a Potentially