Which enzyme catalyzes cGMP breakdown reaction and terminates the signaling process involving this molecule?
A) adenylyl cyclase
B) guanylyl cyclase
C) phosphodiesterase
D) protein kinase A

Question

Quizplus · Accepted Answer

Phosphodiesterase is the enzyme that catalyzes the breakdown of cGMP, hence terminating the signaling process involving this molecule. Adenylyl cyclase and guanylyl cyclase are enzymes involved in the synthesis of cAMP and cGMP respectively. Protein kinase A is a downstream effector in the cAMP signaling pathway, not the cGMP pathway.

Which Enzyme Catalyzes CGMP Breakdown Reaction and Terminates the Signaling