Your niece has been diagnosed with Diamond-Blackfan anemia, an extremely rare disorder of the bone marrow that causes people have a low red blood cell (RBC) count. The disease is classified as a ribosomal protein disease, meaning that one or more of the genes involved in ribosome production is/are mutated, and the ribosomes are not synthesized properly. Although it is not currently understood why mutations in ribosome biosynthesis affect blood cell formation particularly, you are able to help your sister understand the role of ribosomes in the cell and the consequence of ribosome failure, so that she has a better grasp of her child's condition.
-Which of the following statements would NOT be good information for your sister?
A) Ribosomes have two subunits-a large subunit and a small subunit.
B) Ribosomes catalyze peptide bond formation between amino acids.
C) Bacterial ribosomes and eukaryote ribosomes are identical.
D) Protein synthesis is an anabolic reaction and requires ATP.
E) Protein synthesis takes place in the cytoplasm of a cell.

Question

Your niece has been diagnosed with Diamond-Blackfan anemia, an extremely rare disorder of the bone marrow that causes people have a low red blood cell (RBC) count. The disease is classified as a ribosomal protein disease, meaning that one or more of the genes involved in ribosome production is/are mutated, and the ribosomes are not synthesized properly. Although it is not currently understood why mutations in ribosome biosynthesis affect blood cell formation particularly, you are able to help your sister understand the role of ribosomes in the cell and the consequence of ribosome failure, so that she has a better grasp of her child's condition. 
-Which of the following statements would NOT be good information for your sister?
A) Ribosomes have two subunits-a large subunit and a small subunit.
B) Ribosomes catalyze peptide bond formation between amino acids.
C) Bacterial ribosomes and eukaryote ribosomes are identical.
D) Protein synthesis is an anabolic reaction and requires ATP.
E) Protein synthesis takes place in the cytoplasm of a cell.

Quizplus · Accepted Answer

This statement is not entirely accurate. Although bacterial and eukaryotic ribosomes share some similarities, they are not identical. Bacterial ribosomes are smaller and have slightly different protein and RNA components than eukaryotic ribosomes.

Your Niece Has Been Diagnosed with Diamond-Blackfan Anemia, an Extremely