During cell injury caused by hypoxia,an increase in the osmotic pressure occurs within the cell because:
A) Plasma proteins enter the cell.
B) The adenosine triphosphatase (ATPase)-driven pump is stronger during hypoxia.
C) Sodium chloride enters the cell.
D) An influx of glucose occurs through the injured cell membranes.

Question

Quizplus · Accepted Answer

In hypoxic injury,movement of fluid and ions into the cell is associated with acute failure of metabolism and a loss of ATP production.Normally,the pump that transports sodium ions out of the cell is maintained by the presence of ATP and ATPase,the active-transport enzyme.In metabolic failure caused by hypoxia,reduced ATP and ATPase levels permit sodium to accumulate in the cell,whereas potassium diffuses outward.The increase of intracellular sodium increases osmotic pressure,which draws more water into the cell.(Transport mechanisms are described in Chapter 1.)The remaining options do not accurately describe the cell injury that results in increased osmotic pressure caused by hypoxia.

During Cell Injury Caused by Hypoxia,an Increase in the Osmotic