In hypoxic injury,sodium enters the cell and causes swelling because:
A) The cell membrane permeability increases for sodium during periods of hypoxia.
B) ATP is insufficient to maintain the pump that keeps sodium out of the cell.
C) The lactic acid produced by the hypoxia binds with sodium in the cell.
D) Sodium cannot be transported to the cell membrane during hypoxia.

Question

Quizplus · Accepted Answer

In hypoxic injury,movement of fluid and ions into the cell is associated with acute failure of metabolism and a loss of ATP production.Normally,the presence of ATP and ATPase,the active-transport enzyme,maintains the pump that transports sodium ions out of the cell.In metabolic failure caused by hypoxia,reduced ATP and ATPase levels permit sodium to accumulate in the cell,whereas potassium diffuses outward.The other options do not accurately describe the cause of the swelling caused by hypoxia.

In Hypoxic Injury,sodium Enters the Cell and Causes Swelling Because