Indicate whether each of the following histone modifications adds a negative charge to the histone (A), removes a positive charge from the histone (B), or does neither of these (C). Your answer would be a four-letter string composed of letters A, B, and C only, e.g. CABA.
( ) H3 lysine 9 acetylation
( ) H3 serine 10 phosphorylation
( ) H3 lysine 4 trimethylation
( ) H3 lysine 9 trimethylation

Question

Indicate whether each of the following histone modifications adds a negative charge to the histone (A), removes a positive charge from the histone (B), or does neither of these (C). Your answer would be a four-letter string composed of letters A, B, and C only, e.g. CABA.
( )	H3 lysine 9 acetylation
( )	H3 serine 10 phosphorylation
( )	H3 lysine 4 trimethylation
( )	H3 lysine 9 trimethylation

Quizplus · Accepted Answer

Histone H3 lysine 9 acetylation removes a positive charge from the histone and is associated with actively transcribed genes and open chromatin conformations; similar effects arise from H3 serine 10 phosphorylation, which adds a negative charge to the histone. Trimethylation of H3 lysine 4 is also associated with active genes. It keeps the positive charge on the lysine, as does the H3 lysine 9 trimethylation that is associated with silenced genes and heterochromatin formation.

Indicate Whether Each of the Following Histone Modifications Adds a Negative