A gene that had been turned off in a liver cell has just been induced to be highly expressed as the cell responds to a new metabolic load. What observations do you expect to accompany this change?

Question

Quizplus · Accepted Answer

High transcriptional activity is accompanied by the recruitment of a large number of proteins including the RNA polymerase transcription machinery. This may coincide with the migration of the gene from its previous environment in the chromosome territory out toward the foci of active transcription. The chromatin profile of the gene is also expected to change toward a more open state.

A Gene That Had Been Turned Off in a Liver