Imagine a gene encoding a pre-mRNA with twelve exons, ten of which can be alternatively spliced in vivo. Assuming that alternative splicing for this RNA only occurs through exon skipping, how many different proteins can possibly be made from this pre-mRNA as a result of alternative splicing?
A) About 10
B) About 20
C) About 100
D) About 200
E) About 1000

Question

Quizplus · Accepted Answer

Each alternative exon is either skipped or retained, possibly creating 2¹⁰ (= ~1000) different mature mRNAs.

Imagine a Gene Encoding a Pre-MRNA with Twelve Exons, Ten