When a promoter p is not saturated with bound regulatory protein A, doubling the total concentration of A would …
A) increase steady-state [A:p] exactly twofold.
B) increase steady-state [A:p] over twofold.
C) increase steady-state [A:p] less than twofold.
D) decrease steady-state [A:p] approximately twofold.
E) decrease steady-state [A:p] over twofold.

Question

Quizplus · Accepted Answer

At steady state, [A:p] = K[A][pᵀ]/(1 + K[A]). Therefore, doubling [A] increases [A:p], but not by twofold. Please refer to the equations in Figure 8-72.

When a Promoter P Is Not Saturated with Bound Regulatory