Indicate true (T) and false (F) statements below regarding secretory vesicles. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTF.
( ) Proteins destined for secretory vesicles (for regulated secretion) often aggregate in the lumen of the TGN.
( ) The lumen of secretory vesicles is generally less acidic than the lumen of the TGN from which they originate.
( ) A secretory vesicle starts recycling Golgi components only after it has budded from the TGN and its coat proteins have disassembled.
( ) Secretory vesicles recycle Golgi components to the TGN in small clathrin-coated vesicles.

Question

Indicate true (T) and false (F) statements below regarding secretory vesicles. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTF.
( )	Proteins destined for secretory vesicles (for regulated secretion) often aggregate in the lumen of the TGN.
( )	The lumen of secretory vesicles is generally less acidic than the lumen of the TGN from which they originate.
( )	A secretory vesicle starts recycling Golgi components only after it has budded from the TGN and its coat proteins have disassembled.
( )	Secretory vesicles recycle Golgi components to the TGN in small clathrin-coated vesicles.

Quizplus · Accepted Answer

Secretory vesicles bud from the trans Golgi network (TGN) in a process that involves highly concentrating the enclosed secretory proteins into aggregates. The immature vesicles become more and more acidic, fuse with each other, and send clathrin-coated vesicles back to the TGN, sometimes even before they have completed budding from the TGN themselves.

Indicate True (T) and False (F) Statements Below Regarding Secretory