Indicate whether each of the following conditions favors a larger (L) or smaller (S) tissue or body size. Your answer would be a four-letter string composed of letters L and S only, e.g. SSSS.
( ) Hippo overexpression
( ) Insulin-like growth factor overexpression
( ) Myostatin deletion
( ) Growth hormone deficiency

Question

Indicate whether each of the following conditions favors a larger (L) or smaller (S) tissue or body size. Your answer would be a four-letter string composed of letters L and S only, e.g. SSSS.
( )	Hippo overexpression
( )	Insulin-like growth factor overexpression
( )	Myostatin deletion
( )	Growth hormone deficiency

Quizplus · Accepted Answer

Growth hormone stimulates growth, and its deficiency leads to a smaller body size. It acts by inducing the expression of insulin-like growth factor, overexpression of which may lead to a larger body size in an animal. Myostatin specifically inhibits the growth and proliferation of myoblasts; consequently, loss of myostatin results in greatly enlarged muscle tissue. The Hippo pathway inhibits organ and body growth in general; overexpression of Hippo, an upstream component of this pathway, inhibits growth.

Indicate Whether Each of the Following Conditions Favors a Larger