Consider the embryonic cerebral cortex of a mammal. Near which side of the cortex are the cell bodies of radial glial cells located? To which side of the cortex do the first-born neurons eventually migrate?
A) Inner surface; inner surface
B) Inner surface; outer surface
C) Outer surface; inner surface
D) Outer surface; outer surface

Question

Quizplus · Accepted Answer

The radial glial cells form a scaffold in the developing cortex to guide the migrating neurons to their destined layer. The first-born neurons migrate and settle closest to the lumenal (inner) surface of the cortex, whereas last-born neurons crawl past them and settle in outer layers. The radial glial cells divide near the lumenal surface (where their cell bodies are located) to give rise to neurons and glia.

Consider the Embryonic Cerebral Cortex of a Mammal