Indicate true (T) and false (F) statements below regarding viral cell entry. Your answer would be a four-letter string composed of letters T and F only, e.g. FFTF.
( ) Endocytosis inhibitors can block HIV entry but not influenza virus entry.
( ) Adenovirus infection is blocked by membrane-fusion inhibitors.
( ) Individuals with a defective CCR5 gene are more susceptible to HIV infection.
( ) Most viruses enter the host cell by phagocytosis.

Question

Indicate true (T) and false (F) statements below regarding viral cell entry. Your answer would be a four-letter string composed of letters T and F only, e.g. FFTF.
( )	Endocytosis inhibitors can block HIV entry but not influenza virus entry.
( )	Adenovirus infection is blocked by membrane-fusion inhibitors.
( )	Individuals with a defective CCR5 gene are more susceptible to HIV infection.
( )	Most viruses enter the host cell by phagocytosis.

Quizplus · Accepted Answer

Some enveloped viruses such as human immunodeficiency virus (HIV) fuse with the host-cell plasma membrane for entry; others such as influenza A virus fuse with a host-cell membrane after endocytosis. Inhibition of endocytosis is therefore expected to mostly affect influenza virus entry. Nonenveloped viruses such as adenovirus enter the cell via endocytosis followed by endosomal membrane disruption. Individuals with a defective CCR5 gene are less susceptible to HIV infection, as the virus requires CCR5 to enter some host cells. Most viruses enter the host cell by endocytosis or macropinocytosis.

Indicate True (T) and False (F) Statements Below Regarding Viral