Which of the following is true about clamp loaders?
A) They are pentameric enzymes
B) They serve to open up the sliding clamp and insert the DNA
C) They are ATPases
D) All of these

Question

Quizplus · Accepted Answer

Clamp loaders are complex proteins that play a crucial role in DNA replication. They are indeed ATPases, which means they hydrolyze ATP to provide the energy necessary for their function. Their primary role is to open up the sliding clamp, a ring-shaped protein that encircles DNA, and then insert the DNA into this ring. This process is essential for the replication machinery to maintain a strong association with the DNA strand. Furthermore, while the composition of clamp loaders can vary among organisms, they often function as a complex that can be described as pentameric, meaning composed of five subunits, among other configurations. Therefore, all the statements provided are true about clamp loaders.

Which of the Following Is True About Clamp Loaders