Which of the activities of DNA Polymerase I is most important in its role of proofreading?
A) Polymerase activity.
B) Ability to nick intact double stranded DNA.
C) 5' → 3' exonuclease.
D) 3' → 5' exonuclease.
E) None of these is used for proofreading.

Question

Quizplus · Accepted Answer

The 3' → 5' exonuclease activity of DNA Polymerase I is crucial for its proofreading function, allowing it to remove incorrectly paired nucleotides during DNA replication.

Which of the Activities of DNA Polymerase I Is Most