A scientist is investigating the structure of several hormone receptors. From a homogenized tissue sample, receptor proteins are extracted and purified. According to detailed structural study, one of the proteins has a 30-amino acid pattern that coordinates a zinc molecule, as illustrated in the picture below. A receptor for which of the following hormones was most likely isolated in this experiment?

Question

A scientist is investigating the structure of several hormone receptors. From a homogenized tissue sample, receptor proteins are extracted and purified. According to detailed structural study, one of the proteins has a 30-amino acid pattern that coordinates a zinc molecule, as illustrated in the picture below.  A receptor for which of the following hormones was most likely isolated in this experiment?

Quizplus · Accepted Answer

Eductional Objective: Zinc-finger motifs are made up of chains of amino acids linked together around a zinc atom by cysteine and histidine residues. Many transcription factors employ them to bind DNA and change the activity of target genes because they recognize certain DNA sequences. Intracellular receptors with zinc-finger binding domains that bind steroids, thyroid hormone, and fat-soluble vitamins serve directly as transcription factors.

A Scientist Is Investigating the Structure of Several Hormone Receptors