A 34-year-old woman arrives at the emergency department in the early morning, confused, trembling, and sweating. Her spouse claims she did not wake up to her alarm clock and was difficult to awaken. The patient has experienced comparable experiences in the morning before eating and after exercising in the last week. The patient's medical history is ordinary. The blood pressure is 135/95 mm Hg, the pulse is 110 beats per minute, and the respirations are 24/ minute. The patient is receptive to voice but does not obey directions. The assessment of the cranial nerves, muscular tone, and deep tendon reflexes are all normal. The glucose level on a bedtime fingerstick is 35 mg/dL. The patient receives an intravenous infusion of glucose, which improves her mental condition quickly. Further evaluation reveals that her episodes of hypoglycemia are due to increased levels of an endogenous hormone. This hormonal imbalance is most likely causing the patient's symptoms by stimulating which of the following conversions?

Question

A 34-year-old woman arrives at the emergency department in the early morning, confused, trembling, and sweating. Her spouse claims she did not wake up to her alarm clock and was difficult to awaken. The patient has experienced comparable experiences in the morning before eating and after exercising in the last week. The patient's medical history is ordinary. The blood pressure is 135/95 mm Hg, the pulse is 110 beats per minute, and the respirations are 24/ minute. The patient is receptive to voice but does not obey directions. The assessment of the cranial nerves, muscular tone, and deep tendon reflexes are all normal. The glucose level on a bedtime fingerstick is 35 mg/dL. The patient receives an intravenous infusion of glucose, which improves her mental condition quickly. Further evaluation reveals that her episodes of hypoglycemia are due to increased levels of an endogenous hormone.  This hormonal imbalance is most likely causing the patient's symptoms by stimulating which of the following conversions?

Quizplus · Accepted Answer

Eductional Objective: Phosphofructokinase-1 (PFK1) catalyzes the rate-limiting step in glycolysis, and fructose 2,6-bisphosphate is the most effective PFK1 stimulator. Insulin stimulates glycolysis by increasing the synthesis of fructose 2,6-bisphosphate by phosphofructokinase-2 (PFK2).

A 34-Year-Old Woman Arrives at the Emergency Department in the Early