A 55-year-old farmer is taken to the emergency room after his daughter discovered him confused and disoriented in his home tool shed. He is otherwise healthy and does not require any drugs. On physical examination, the blood pressure is 110/70 mm Hg and the pulse rate is 50 / minute. The patient's pupils are symmetric, 2 mm in diameter, and light reactive. His eyes are crying up a lot. On lung auscultation, there are scattered wheezes bilaterally. The patient's skin is clammy, and he is excessively sweating. Which of the following stages at the neuromuscular junction is most likely impaired in his presentation?

Question

A 55-year-old farmer is taken to the emergency room after his daughter discovered him confused and disoriented in his home tool shed. He is otherwise healthy and does not require any drugs. On physical examination, the blood pressure is 110/70 mm Hg and the pulse rate is 50 / minute. The patient's pupils are symmetric, 2 mm in diameter, and light reactive. His eyes are crying up a lot. On lung auscultation, there are scattered wheezes bilaterally. The patient's skin is clammy, and he is excessively sweating. Which of the following stages at the neuromuscular junction is most likely impaired in his presentation?

Quizplus · Accepted Answer

Eductional Objective: Organophosphates are cholinesterase inhibitors that are widely used as pesticides in agriculture.  They inhibit the breakdown of acetylcholine, leading to a state of cholinergic excess.  Symptoms of organophosphate poisoning include salivation, lacrimation, diaphoresis, bradycardia, and bronchospasm.

A 55-Year-Old Farmer Is Taken to the Emergency Room After