A 7-year-old boy is brought to the emergency department due to lethargy and vomiting. He hasn't eaten for approximately 24 hours because he had been on an overnight hiking trip with his family. During the trip, the family lost their food pack while canoeing and had to hike back to their car. The child became weak and was carried for the last mile. None of the family On examination, the patient appears listless. Mild hepatomegaly is noted. Laboratory results are as follows: The patient begins seizing shortly after arriving at the emergency department. Which of the following enzymes is most likely deficient in this patient?

Question

A 7-year-old boy is brought to the emergency department due to lethargy and vomiting. He hasn't eaten for approximately 24 hours because he had been on an overnight hiking trip with his family.  During the trip, the family lost their food pack while canoeing and had to hike back to their car.  The child became weak and was carried for the last mile.  None of the family   On examination, the patient appears listless.  Mild hepatomegaly is noted.  Laboratory results are as follows:  The patient begins seizing shortly after arriving at the emergency department.  Which of the following enzymes is most likely deficient in this patient?

Quizplus · Accepted Answer

Eductional Objective: Impaired beta-oxidation of fatty acids causes hypoglycemia after prolonged fasting and insufficient levels of ketone bodies.  Acyl-CoA dehydrogenase catalyzes the first step in the beta-oxidation pathway and is the most commonly deficient enzyme.

A 7-Year-Old Boy Is Brought to the Emergency Department Due