Researchers researching neural crest cell migration in a human baby see normal activity beginning during the eighth week of embryogenesis, with a brief pause during the 12th week, when migration is generally completed. As a result of this disruption, which of the following structures is most likely to be devoid of innervation?

Question

Quizplus · Accepted Answer

Eductional Objective: Hirschsprung disease is caused by abnormal migration of neural crest cells (ganglion cell precursors) during embryogenesis.  Because neural crest cells migrate caudally down the bowel from the foregut, the rectum is always affected.

Researchers Researching Neural Crest Cell Migration in a Human Baby