Researchers are working on an enzyme-linked immunosorbent assay test for rheumatoid arthritis diagnosis. The test is intended to identify serum antibodies against citrullinated proteins. Two test populations with varying rheumatoid arthritis prevalence are chosen. The researchers want to compare a variety of diagnostic test parameters to assess the test's performance in the two groups. Which of the following performance indicators is most likely to differ between the two test populations?

Question

Quizplus · Accepted Answer

Eductional Objective: Various parameters are used to evaluate the accuracy and usefulness of diagnostic tests. Positive and negative predictive values are influenced by disease prevalence in the target population; sensitivity, specificity, and likelihood ratios are not prevalence-dependent.

Researchers Are Working on an Enzyme-Linked Immunosorbent Assay Test for Rheumatoid