In a group of 1,000 75-year-old women, a test is utilized to identify dementia. The test has an 80 percent sensitivity and a 90 percent specificity. The test is then utilized as a diagnostic tool in two different groups of women of the same age: population 1 has a dementia prevalence of 15%, and population 2 has a dementia prevalence of 30%. Which of the following best illustrates the relationship between the negative predictive values (NPV) and positive predictive values (PPV) from populations 1 and 2?

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Eductional Objective: Predictive values change depending on the prevalence of disease in a study population. As disease prevalence increases, the positive predictive value increases, and the negative predictive value decreases.

In a Group of 1,000 75-Year-Old Women, a Test Is