A 72-year-old man with a history of myocardial infarction is being autopsied. Light microscopy of a section of the left ventricle reveals the following findings: This patient most likely sustained the myocardial infarction during which of the following time frames prior to his death?

Question

A 72-year-old man with a history of myocardial infarction is being autopsied. Light microscopy of a section of the left ventricle reveals the following findings:  This patient most likely sustained the myocardial infarction during which of the following time frames prior to his death?

Quizplus · Accepted Answer

Eductional Objective: Irreversible myocardial ischemia damage causes a succession of predictable morphologic alterations that last from hours to weeks. In response to proinflammatory cytokines (e.g., IL-6, IL-8), neutrophils infiltrate the border zone of the wounded tissue (where myocytes are generally normal) between 1 and 3 days after the initial injury, eventually moving to the center area of the infarct.

A 72-Year-Old Man with a History of Myocardial Infarction Is